Mood & Mental Health

·

Study

High-Dose Psilocybin Changes Mood-Related Genes in Rats

High-Dose Psilocybin Changes Mood-Related Genes in Rats

Psilocybin mushrooms

What they found

A high psilocybin dose boosted genes for mood peptides and serotonin receptors in the rat hypothalamus.

A high psilocybin dose boosted genes for mood peptides and serotonin receptors in the rat hypothalamus.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Journal of Psychopharmacology

Journal of Psychopharmacology

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Mood Shift Molecule

Mood Shift Molecule

A high dose of psilocybin boosted gene expression for mood-related peptides and serotonin receptors in the rat hypothalamus. This suggests psilocybin may reduce stress and depression by rewiring brain signaling at the molecular level.

A high dose of psilocybin boosted gene expression for mood-related peptides and serotonin receptors in the rat hypothalamus. This suggests psilocybin may reduce stress and depression by rewiring brain signaling at the molecular level.

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