Mood & Mental Health

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Review

Inhaled DMT Relieves Depression Faster Than Psilocybin

Inhaled DMT Relieves Depression Faster Than Psilocybin

Psilocybin mushrooms

What they found

Inhaled DMT and 5-MeO-DMT relieved depression within hours, with 87.5% in one trial still in remission after a week.

Inhaled DMT and 5-MeO-DMT relieved depression within hours, with 87.5% in one trial still in remission after a week.

The number

87.5% of patients in one trial staying in full remission after a week

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

DMT; 5-MeO-DMT; psilocybin

DMT; 5-MeO-DMT; psilocybin

Published in

Neuropsychopharmacology

Neuropsychopharmacology

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Better Than Psilocybin

Better Than Psilocybin

Inhaled DMT and 5-MeO-DMT relieved depression within hours, with 87.5% of patients in one trial staying in full remission after a week. By comparison, psilocybin’s effect took longer and faded faster, with only 20% still responding after three months.

Inhaled DMT and 5-MeO-DMT relieved depression within hours, with 87.5% of patients in one trial staying in full remission after a week. By comparison, psilocybin’s effect took longer and faded faster, with only 20% still responding after three months.

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