Brain & Cognition

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Study

Low-Dose Psilocybin Restored Memory in Fragile X Rats

Low-Dose Psilocybin Restored Memory in Fragile X Rats

Psilocybin mushrooms

What they found

Low-dose psilocybin improved object recognition and restored learning deficits in a Fragile X rat model.

Low-dose psilocybin improved object recognition and restored learning deficits in a Fragile X rat model.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Psilocybe spp.

Psilocybe spp.

Compound

psilocybin

psilocybin

Published in

Neuropsychopharmacology

Neuropsychopharmacology

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Plasticity Pathway Boost

Plasticity Pathway Boost

Psilocybin (from Psilocybe spp.) improved novel object recognition performance in a Fragile X rat model, restoring learning and memory deficits after low-dose administration. The cognitive gains suggest psilocybin may support learning and memory through brain-repair signaling, potentially separable from hallucinogenic effects, though evidence remains preclinical.

Psilocybin (from Psilocybe spp.) improved novel object recognition performance in a Fragile X rat model, restoring learning and memory deficits after low-dose administration. The cognitive gains suggest psilocybin may support learning and memory through brain-repair signaling, potentially separable from hallucinogenic effects, though evidence remains preclinical.

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