Mood & Mental Health

·

Study

Many Naturalistic Psilocybin Users Report Sharper Thinking Afterward

Many Naturalistic Psilocybin Users Report Sharper Thinking Afterward

Psilocybin mushrooms

What they found

In over 2,800 people, many reported better mental health after psilocybin; 30% improved greatly while 8% kept struggling.

In over 2,800 people, many reported better mental health after psilocybin; 30% improved greatly while 8% kept struggling.

The number

30% saw big improvements

How solid is it?

Early human

Early human

Human – observational/survey

Human – observational/survey

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Sample size

over 2,800 people

over 2,800 people

Published in

International Journal of Mental Health and Addiction

International Journal of Mental Health and Addiction

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Cognitive Clarity After Psilocybin

Cognitive Clarity After Psilocybin

A large survey of over 2,800 people planning natural psilocybin use found that many reported improved mental health and sharper cognitive flexibility in the weeks and months after. But outcomes varied: while 30% saw big improvements and low substance use, 8% continued struggling with both mental health and substance use. The biggest differences came down to participants' personality traits and mindset going into the experience, highlighting how much set and setting still matter.

A large survey of over 2,800 people planning natural psilocybin use found that many reported improved mental health and sharper cognitive flexibility in the weeks and months after. But outcomes varied: while 30% saw big improvements and low substance use, 8% continued struggling with both mental health and substance use. The biggest differences came down to participants' personality traits and mindset going into the experience, highlighting how much set and setting still matter.

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