Liver & Kidney

·

Study

Matsutake Extract Protected Mouse Livers From Alcohol

Matsutake Extract Protected Mouse Livers From Alcohol

Matsutake

What they found

Matsutake extract lowered liver damage markers ALT, AST and triglycerides in alcohol-exposed mice.

Matsutake extract lowered liver damage markers ALT, AST and triglycerides in alcohol-exposed mice.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Tricholoma matsutake

Tricholoma matsutake

Published in

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Alcohol Damage Control

Alcohol Damage Control

Matsutake mushroom (Tricholoma matsutake) extract significantly lowered liver damage markers ALT, AST, and triglycerides in alcohol-exposed mice while restoring healthier liver structure. The treatment rebalanced 12 liver metabolites and 31 blood metabolites, including glucose, cholesterol, and amino acids tied to energy and detox pathways. It also regulated key alcohol-processing genes (Aldh2, Acox1, Acaa1), directly improving how the body breaks down alcohol and protects liver cells.

Matsutake mushroom (Tricholoma matsutake) extract significantly lowered liver damage markers ALT, AST, and triglycerides in alcohol-exposed mice while restoring healthier liver structure. The treatment rebalanced 12 liver metabolites and 31 blood metabolites, including glucose, cholesterol, and amino acids tied to energy and detox pathways. It also regulated key alcohol-processing genes (Aldh2, Acox1, Acaa1), directly improving how the body breaks down alcohol and protects liver cells.

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