Mood & Mental Health

·

Study

Psilocybin Cut OCD Symptoms in a Small Trial

Psilocybin Cut OCD Symptoms in a Small Trial

Psilocybin mushrooms

What they found

Across 4–8 psilocybin sessions over 8 weeks, 73.3% of participants saw at least a 35% drop in OCD scores and 40% reached remission.

Across 4–8 psilocybin sessions over 8 weeks, 73.3% of participants saw at least a 35% drop in OCD scores and 40% reached remission.

The number

73.3% of participants achieving at least a 35% drop in YBOCS scores

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Journal of Psychopharmacology

Journal of Psychopharmacology

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

OCD Symptom Drop

OCD Symptom Drop

Psilocybin (100–300 µg/kg) given across 4–8 sessions over 8 weeks reduced OCD severity, with 73.3% of participants achieving at least a 35% drop in YBOCS scores and 40% reaching remission. No serious adverse events, psychosis, or increases in suicidal behavior were reported across the trial. Benefits remained substantial at 6 months, showing durable symptom relief after repeated dosing.

Psilocybin (100–300 µg/kg) given across 4–8 sessions over 8 weeks reduced OCD severity, with 73.3% of participants achieving at least a 35% drop in YBOCS scores and 40% reaching remission. No serious adverse events, psychosis, or increases in suicidal behavior were reported across the trial. Benefits remained substantial at 6 months, showing durable symptom relief after repeated dosing.

Tumors Cut 60%, OCD Drops 73%, and Mushrooms vs. Meat

Read the original study ↗

Get Shroom Scan

Next study

SSRI Antidepressants Can Dull Psilocybin Effects ›

Shroom Scan · Every Friday

Get Studies Like This, Translated, Every Week

Ten new studies a week, each boiled down to what it found and why it matters to you. Free, and one click to leave.

See what's inside →