Cancer

·

Study

Mushroom-Coated Selenium Nanodrug Turns Immune Cells Against Liver Cancer

Mushroom-Coated Selenium Nanodrug Turns Immune Cells Against Liver Cancer

Fat pholiota

What they found

Selenium nanoparticles coated with Pholiota adiposa polysaccharides reprogrammed macrophages to fight liver cancer.

Selenium nanoparticles coated with Pholiota adiposa polysaccharides reprogrammed macrophages to fight liver cancer.

How solid is it?

Lab dish

Lab dish

Lab – cell study

Lab – cell study

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Pholiota adiposa

Pholiota adiposa

Compound

PAP-SeNPs

PAP-SeNPs

Published in

International Journal of Biological Macromolecules

International Journal of Biological Macromolecules

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Liver Cancer Treatment

Liver Cancer Treatment

Researchers developed a novel nanodrug using selenium nanoparticles coated with polysaccharides from the mushroom Pholiota adiposa (PAP-SeNPs) to enhance liver cancer treatment. It effectively reprograms immune cells called macrophages from a tumor-supporting state to a tumor-fighting state, boosting the body's immune response against liver cancer.

Researchers developed a novel nanodrug using selenium nanoparticles coated with polysaccharides from the mushroom Pholiota adiposa (PAP-SeNPs) to enhance liver cancer treatment. It effectively reprograms immune cells called macrophages from a tumor-supporting state to a tumor-fighting state, boosting the body's immune response against liver cancer.

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