Cancer

·

Review

Ocean Aspergillus Fungi Produce 200+ Cancer-Fighting Compounds

Ocean Aspergillus Fungi Produce 200+ Cancer-Fighting Compounds

Aspergillus

What they found

Over 200 anticancer compounds from marine Aspergillus have been identified, but only Plinabulin has reached clinical testing.

Over 200 anticancer compounds from marine Aspergillus have been identified, but only Plinabulin has reached clinical testing.

The number

200+ cancer-fighting compounds have been identified

How solid is it?

Review

Review

Narrative review

Narrative review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Aspergillus

Aspergillus

Compound

Terrein; Wentilactone B; Plinabulin

Terrein; Wentilactone B; Plinabulin

Published in

Mycology

Mycology

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Marine Fungi Against Cancer

Marine Fungi Against Cancer

Aspergillus, a common fungus, produces powerful anticancer compounds when found in ocean environments. These compounds mainly come from ocean floor sediments (43%), miscellaneous marine sources (31%), sea sponges (16%), and seaweed (10%). The compounds fall into several chemical categories: organic compounds (25%), terpenoids (21%), peptides (18%), phenolics (17%), polyketides (12%), alkaloids (5%), and steroids (2%). These natural compounds can kill cancer cells while leaving healthy cells unharmed. Two standout compounds include Terrein, which fights ovarian cancer, and Wentilactone B, which attacks liver cancer cells. 200+ cancer-fighting compounds have been identified, but only one, called Plinabulin, has reached clinical testing.

Aspergillus, a common fungus, produces powerful anticancer compounds when found in ocean environments. These compounds mainly come from ocean floor sediments (43%), miscellaneous marine sources (31%), sea sponges (16%), and seaweed (10%). The compounds fall into several chemical categories: organic compounds (25%), terpenoids (21%), peptides (18%), phenolics (17%), polyketides (12%), alkaloids (5%), and steroids (2%). These natural compounds can kill cancer cells while leaving healthy cells unharmed. Two standout compounds include Terrein, which fights ovarian cancer, and Wentilactone B, which attacks liver cancer cells. 200+ cancer-fighting compounds have been identified, but only one, called Plinabulin, has reached clinical testing.

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