Mood & Mental Health

·

Study

Psilocybin and MDMA Reverse Stress-Induced Fear by Calming Immune Cells

Psilocybin and MDMA Reverse Stress-Induced Fear by Calming Immune Cells

Psilocybin mushrooms

What they found

Psilocybin and MDMA reversed stress-induced fear by stopping inflammatory immune cells from entering the brain.

Psilocybin and MDMA reversed stress-induced fear by stopping inflammatory immune cells from entering the brain.

How solid is it?

Unclear

Unclear

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin; MDMA

psilocybin; MDMA

Published in

Nature

Nature

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Calming Fear

Calming Fear

Psilocybin and MDMA helped reverse stress-induced fear by stopping inflammatory immune cells from invading the brain and restoring balance in key fear circuits. The study shows psychedelics may ease trauma by rewiring how the brain and immune system interact.

Psilocybin and MDMA helped reverse stress-induced fear by stopping inflammatory immune cells from invading the brain and restoring balance in key fear circuits. The study shows psychedelics may ease trauma by rewiring how the brain and immune system interact.

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