Mood & Mental Health

·

Review

Psilocybin Brings Fast, Lasting Relief in Treatment-Resistant Depression

Psilocybin Brings Fast, Lasting Relief in Treatment-Resistant Depression

Psilocybin mushrooms

What they found

In treatment-resistant depression, 67% responded after one psilocybin dose and 30% reached full remission, with effects up to six months.

In treatment-resistant depression, 67% responded after one psilocybin dose and 30% reached full remission, with effects up to six months.

The number

response rates were 67% after one dose, with 30% achieving full remission

How solid is it?

Review

Review

Narrative review

Narrative review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

assets.cureus.com

assets.cureus.com

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Depression Research

Depression Research

Psilocybin rapidly reduces depression symptoms, with effects lasting for up to six months. In patients with treatment-resistant depression, response rates were 67% after one dose, with 30% achieving full remission. It also eased end-of-life anxiety in terminally ill patients.

Psilocybin rapidly reduces depression symptoms, with effects lasting for up to six months. In patients with treatment-resistant depression, response rates were 67% after one dose, with 30% achieving full remission. It also eased end-of-life anxiety in terminally ill patients.

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