Mood & Mental Health

·

Study

Psilocybin Eased Anxiety and Depression in Ovarian Cancer Patients

Psilocybin Eased Anxiety and Depression in Ovarian Cancer Patients

Psilocybin mushrooms

What they found

In a small Phase II trial, psilocybin improved mental health scores 14.3 versus 7.1 for placebo in ovarian cancer patients.

In a small Phase II trial, psilocybin improved mental health scores 14.3 versus 7.1 for placebo in ovarian cancer patients.

The number

14.3 versus 7.1 on a standard scale

How solid is it?

Early human

Early human

Human – RCT

Human – RCT

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin; niacin

psilocybin; niacin

Sample size

7 patients (3 psilocybin, 4 placebo)

7 patients (3 psilocybin, 4 placebo)

Published in

ijgc.bmj.com

ijgc.bmj.com

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Ovarian Cancer Patients and Mental Health

Ovarian Cancer Patients and Mental Health

A Phase II clinical trial showed psilocybin therapy dramatically reduced anxiety and depression in ovarian cancer patients. Three patients received a single moderate dose of psilocybin (21mg adjusted for body weight) while four got vitamin B3 (250mg niacin) as placebo - all with counseling before and after. The psilocybin group's mental health scores improved by more than 7 points compared to placebo (14.3 versus 7.1 on a standard scale). Benefits started the day after treatment and grew stronger over the full 6-week study, while the placebo group's improvements were temporary.

A Phase II clinical trial showed psilocybin therapy dramatically reduced anxiety and depression in ovarian cancer patients. Three patients received a single moderate dose of psilocybin (21mg adjusted for body weight) while four got vitamin B3 (250mg niacin) as placebo - all with counseling before and after. The psilocybin group's mental health scores improved by more than 7 points compared to placebo (14.3 versus 7.1 on a standard scale). Benefits started the day after treatment and grew stronger over the full 6-week study, while the placebo group's improvements were temporary.

🧬 Cancer-Fighting Mushrooms, Heart Health, and Psilocybin for PTSD Relief

Read the original study ↗

Get Shroom Scan

Next study

Psilocybin for Anorexia Shows Promise and Limits in Pilot ›

Shroom Scan · Every Friday

Get Studies Like This, Translated, Every Week

Ten new studies a week, each boiled down to what it found and why it matters to you. Free, and one click to leave.

See what's inside →