Mood & Mental Health

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Review

Psilocybin Led to Depression Remission in Up to 67%

Psilocybin Led to Depression Remission in Up to 67%

Psilocybin mushrooms

What they found

One or two psilocybin doses led to remission in up to 67% of people with depression, even alongside SSRIs.

One or two psilocybin doses led to remission in up to 67% of people with depression, even alongside SSRIs.

The number

remission in up to 67%

How solid is it?

Review

Review

Narrative review

Narrative review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Drugs

Drugs

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Psilocybin for Depression

Psilocybin for Depression

One or two doses of psilocybin led to remission in up to 67% of people with depression. It remained effective even when patients stayed on SSRIs, easing concerns about drug interactions. Side effects were mostly mild, but long-term safety still needs more research.

One or two doses of psilocybin led to remission in up to 67% of people with depression. It remained effective even when patients stayed on SSRIs, easing concerns about drug interactions. Side effects were mostly mild, but long-term safety still needs more research.

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