A new review from Monash University explores how psilocybin may treat anorexia nervosa by improving cognitive flexibility and reward processing, two major challenges in the disorder. It highlights how psilocybin’s effects on both serotonin and dopamine systems help rewire brain circuits like the prefrontal cortex and nucleus accumbens. Early evidence from both human and rodent studies points to meaningful, lasting neuroplastic changes that could offer hope for this difficult-to-treat condition