Liver & Kidney

·

Study

Psilocybin Plus Semaglutide Improves Fatty Liver in Mice

Psilocybin Plus Semaglutide Improves Fatty Liver in Mice

Psilocybin mushrooms

What they found

Combining psilocybin and semaglutide reduced liver fat and improved insulin sensitivity in mice with fatty liver disease.

Combining psilocybin and semaglutide reduced liver fat and improved insulin sensitivity in mice with fatty liver disease.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin; semaglutide

psilocybin; semaglutide

Published in

Digestive and Liver Disease

Digestive and Liver Disease

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Fatty Liver Disease

Fatty Liver Disease

A study in mice with metabolic-associated fatty liver disease (MASLD) found that combining psilocybin and semaglutide significantly improved metabolism, reduced liver fat, and enhanced insulin sensitivity. The combo also protected muscle function, suggesting it could offer advantages over single-drug treatments for metabolic disorders.

A study in mice with metabolic-associated fatty liver disease (MASLD) found that combining psilocybin and semaglutide significantly improved metabolism, reduced liver fat, and enhanced insulin sensitivity. The combo also protected muscle function, suggesting it could offer advantages over single-drug treatments for metabolic disorders.

Flu Defense, Joint Health, and Psilocybin’s Metabolic Edge

Read the original study ↗

Get Shroom Scan

Next study

Single 25 mg Psilocybin Dose Kept Depression Away for 189 Days ›

Shroom Scan · Every Friday

Get Studies Like This, Translated, Every Week

Ten new studies a week, each boiled down to what it found and why it matters to you. Free, and one click to leave.

See what's inside →