Liver & Kidney

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Study

Reishi and Polyporus Extracts Reduce Kidney Scarring Markers in Pet Cells

Reishi and Polyporus Extracts Reduce Kidney Scarring Markers in Pet Cells

Reishi, Polyporus

What they found

Reishi and polyporus extracts suppressed fibrosis markers in canine and feline kidney cells, more strongly combined.

Reishi and polyporus extracts suppressed fibrosis markers in canine and feline kidney cells, more strongly combined.

The number

non-toxic up to 5 mg/mL

How solid is it?

Lab dish

Lab dish

In vitro (lab dish)

In vitro (lab dish)

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Ganoderma lucidum, Polyporus umbellatus

Ganoderma lucidum, Polyporus umbellatus

Published in

Veterinary Research Communications

Veterinary Research Communications

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Anti-Scarring Effect

Anti-Scarring Effect

Reishi mushroom (Ganoderma lucidum) and polyporus mushroom (Polyporus umbellatus) extracts suppressed key fibrosis markers, with combined treatment showing stronger inhibition than either alone. Both extracts were non-toxic up to 5 mg/mL and increased kidney cell viability in canine and feline models. This points to reduced tissue scarring and better organ protection by directly blocking fibrosis-driving pathways.

Reishi mushroom (Ganoderma lucidum) and polyporus mushroom (Polyporus umbellatus) extracts suppressed key fibrosis markers, with combined treatment showing stronger inhibition than either alone. Both extracts were non-toxic up to 5 mg/mL and increased kidney cell viability in canine and feline models. This points to reduced tissue scarring and better organ protection by directly blocking fibrosis-driving pathways.

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