Mood & Mental Health

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Study

Whole Magic Mushroom Extract Beats Pure Psilocybin in OCD-like Mice

Whole Magic Mushroom Extract Beats Pure Psilocybin in OCD-like Mice

Psilocybin mushrooms

What they found

A single dose of whole psychedelic mushroom extract reduced compulsive behavior in mice for up to 7 weeks, matching or beating pure psilocybin.

A single dose of whole psychedelic mushroom extract reduced compulsive behavior in mice for up to 7 weeks, matching or beating pure psilocybin.

The number

up to 7 weeks

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin; baeocystin; norbaeocystin

psilocybin; baeocystin; norbaeocystin

Published in

Molecular Psychiatry

Molecular Psychiatry

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Whole Mushroom Advantage

Whole Mushroom Advantage

In an OCD-like mouse model, a single dose of psychedelic mushroom extract reduced compulsive grooming and anxiety-like behaviors for up to 7 weeks, matching or outperforming pure psilocybin. Researchers suggest this is due to the entourage effect, where compounds like baeocystin and norbaeocystin enhance the therapeutic impact.

In an OCD-like mouse model, a single dose of psychedelic mushroom extract reduced compulsive grooming and anxiety-like behaviors for up to 7 weeks, matching or outperforming pure psilocybin. Researchers suggest this is due to the entourage effect, where compounds like baeocystin and norbaeocystin enhance the therapeutic impact.

Faster Thinking, Safer Cordyceps, and a Psilocybin Milestone

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